“Members of my team, led by Dr. Annik Prat and Dr. Anna Roubtsova, discovered that PCSK9 also regulates fatty acids,” explains Dr. Seidah. “They investigated its role in the metabolism of body fat, and found that PCSK9 is pivotal in regulating cholesterol and fat metabolism: it maintains high circulating cholesterol levels, but it also limits fat generation.”
In another study, the researchers uncovered further data on PCSK9′s mechanism of action and functional structure. Their data showed that a part of PCSK9 inhibits its own function, and that acidic pH levels affect the degradation of bad cholesterol receptors.large pet carrier Another advantage of these bulbs is that it lasts for a very long time and is quite strong compared to ordinary bulbs. These bulbs do not shatter as it is made of epoxy case.
In a third study, the team discovered that two other PCSK enzymes, Furin (PCSK3) and PC5/6 (PCSK5), reduce the level of active PCSK9. “They were able to demonstrate how enzymes of the PCSK family communicate with one another and found that liver-derived Furin cuts PCSK9 and inactivates it,” adds Dr. Seidah. “This provided genetic evidence for the mechanism behind the functioning of a mutant gene found in some human hypercholesterolemic patients.”
An important enzyme for osteoporosis, especially for women after menopause
In another study, the researchers uncovered further data on PCSK9′s mechanism of action and functional structure. Their data showed that a part of PCSK9 inhibits its own function, and that acidic pH levels affect the degradation of bad cholesterol receptors.large pet carrier Another advantage of these bulbs is that it lasts for a very long time and is quite strong compared to ordinary bulbs. These bulbs do not shatter as it is made of epoxy case.
In a third study, the team discovered that two other PCSK enzymes, Furin (PCSK3) and PC5/6 (PCSK5), reduce the level of active PCSK9. “They were able to demonstrate how enzymes of the PCSK family communicate with one another and found that liver-derived Furin cuts PCSK9 and inactivates it,” adds Dr. Seidah. “This provided genetic evidence for the mechanism behind the functioning of a mutant gene found in some human hypercholesterolemic patients.”
An important enzyme for osteoporosis, especially for women after menopause
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